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12:12 intermittent fasting

An overnight schedule with 12 hours for meals and 12 without eating. It can describe an existing routine rather than a new diet.

12h

Fast

12h

Eating window

Start 12:12 timer

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  • Not medical advice

By FastWindowTimer · Published: 2026-06-21 · Content updated: · Not individually medically reviewed — see editorial policy

Example schedule

  1. Eating window opens at 8:00 AM

    First planned meal time.

  2. Eating window closes at 8:00 PM

    Last planned meal time.

  3. Fast until 8:00 AM the next day

    12-hour fasting window begins.

What research does—and does not—show about 12:12

These trials ask different questions: one directly includes 12:12, one uses a 12-hour control, and one tests 16:8. Read the actual comparison before applying a result to a different schedule.

Three trials with different questions and comparison conditions; not a systematic review.
Study, design and participantsWhat was comparedWhat was measured or foundWhat this cannot establish
Sampieri et al. (2024)

Eight-week randomized parallel trial with four groups.

41 metabolically healthy adults aged 18–65 without regular structured exercise.

12:12 (08:00–20:00), 14:10, 16:8 and an unrestricted routine; participants were asked to maintain habitual calorie intake.The authors reported no significant body-composition changes in the 12:12 group and no significant changes in measured blood markers across the groups.Small groups and short follow-up; food intake and adherence were self-reported. This does not establish long-term effects, individual suitability or that a longer fast is better for the reader.
Sutton et al. (2018)

Randomized crossover controlled-feeding trial; five weeks per schedule.

Eight men with prediabetes completed both schedules.

An early six-hour eating window, with dinner before 15:00, versus a 12-hour eating window. The 12-hour window was the control.The authors reported differences in insulin sensitivity and blood pressure favoring the early six-hour condition.Small, specific group; timing and window length changed together. This does not show that 12:12 improves health, or recommend the six-hour condition to readers.
Lowe et al. — TREAT (2020)

Twelve-week randomized trial; data from 116 adults were analyzed.

Adults aged 18–64 with overweight or obesity; eligibility exclusions limit generalization.

Eating from 12:00 to 20:00 (16:8) versus three structured meals per day. The control was not a prescribed 12:12 schedule.Weight change did not differ significantly between groups. Some additional measurements came from an in-person subgroup.Tests 16:8, not the effects of 12:12. A nonsignificant difference does not prove that every schedule has identical effects.

These studies do not establish a general health benefit of 12:12. A nonsignificant finding also does not prove that a schedule has no effect. This is a focused comparison, not a systematic review of every study. Clock-time examples do not predict personal health outcomes.

Calculate an example 12-hour window

Planning considerations

  • Breakfast and dinner 12 hours apart: 08:00–20:00.
  • Use this page to compare timing constraints; suitability requires your own circumstances and, when needed, professional advice.

Practical tradeoffs

Practical use

  • Allows breakfast, lunch and dinner without compressing meals into the afternoon.

Constraints

  • Late snacks or an early breakfast shorten the overnight interval.
  • Do not alter prescribed medication or ignore symptoms to complete a window.

Sources

  1. Sampieri et al. — Impact of daily fasting duration (Journal of Translational Medicine, 2024) (opens in a new tab)

    What this source supports: Directly includes a 12:12 arm, an unrestricted comparator and the reported eight-week results.

    What it cannot establish: Small, selected adult population; short duration and self-reported dietary intake and adherence limit generalization.

    Source checked:

  2. Sutton et al. — Early Time-Restricted Feeding (Cell Metabolism, 2018) (opens in a new tab)

    What this source supports: The trial compares early six-hour feeding with a 12-hour control in eight male completers with prediabetes.

    What it cannot establish: Does not test 12:12 against an unrestricted routine or establish individual suitability; short, small crossover study.

    Source checked:

  3. Lowe et al. — The TREAT Randomized Clinical Trial (JAMA Internal Medicine, 2020) (opens in a new tab)

    What this source supports: Reports the 16:8 intervention, three-meal comparator, 12-week duration, analyzed population and between-group weight result.

    What it cannot establish: Not a 12:12 efficacy trial; eligibility criteria and subgroup measurements limit generalization.

    Source checked:

  4. Cleveland Clinic — What Is Intermittent Fasting? (opens in a new tab)

    What this source supports: Describes daily time-restricted eating and the weekly 5:2 pattern. The example clock times on this page are arithmetic illustrations. It is background context, not a trial of this exact schedule.

    What it cannot establish: Does not demonstrate that a longer fasting window is better or establish individual suitability.

    Source checked:

  5. Cleveland Clinic — 6 Tips for Fasting Safely (opens in a new tab)

    What this source supports: Discusses planning, hydration, medication and avoiding extreme fasting.

    What it cannot establish: General clinical education, not approval of this exact schedule for the reader.

    Source checked:

Frequently asked questions

Does 12:12 require skipping breakfast?
No. An 08:00–20:00 eating window includes breakfast. The notation only defines the interval; it does not prescribe calories or food choices.
What does this schedule tell me about my body?
Only the intended eating and fasting times. It does not measure insulin, ketones, autophagy, or the nutritional adequacy of your meals.
What if the schedule does not fit my day?
Choose a wider eating window or regular meal times. You do not need to compensate for a missed target by extending the next fast.

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